Table 4. Distribution of the 822 bp deletion of mtDNA in major mtDNA haplogroups among male cigarette smoking subjects pooled from cases and controlsa.
| MtDNA haplogroups | Del (n = 138) (%) | Non-Del (n = 290) (%) | p value (X 2) | Adjusted p valueb | OR (95% CI)b |
| A (n = 35) | 8 (5.80) | 27 (9.31) | 0.215 | 0.243 | 0.613(0.270–1.394) |
| B (n = 83) | 25 (18.12) | 58 (20.00) | 0.645 | 0.519 | 0.842(0.498–1.422) |
| M8 (n = 38) | 9 (6.52) | 29 (10.00) | 0.237 | 0.304 | 0.662(0.301–1.454) |
| G (n = 31) | 8 (5.80) | 23 (7.93) | 0.426 | 0.551 | 0.774(0.334–1.794) |
| F (n = 65) | 27 (19.57) | 38 (13.10) | 0.082 | 0.066 | 1.672(0.967–2.889) |
| D (n = 90) | 46 (33.33) | 44 (15.17) | <0.001 | <0.001 | 2.752(1.699–4.456) |
| M7 (n = 52) | 12 (8.70) | 40 (13.79) | 0.131 | 0.132 | 0.592(0.299–1.171) |
| Others (n = 34) | 3 (2.17) | 31 (10.69) | NA | NA | NA |
Del, deletion.
For multiple comparisons, P value was set <0.05/2×(n−1) (n = 8).
a
, Cigarette smoking subjects who had any history of cigarette smoking.
b
, ORs (95% CIs) and p value determined by multivariate logistic regression analysis adjusted for age.