Table 2. Different primers used for detecting EBV prevalence in PCR analyses.
| Amplification fragments | No. of studiesa | No. of cases | Prevalence | Prevalence (%)(95% CI) | Adjusted ORb |
| Bam H1W | 12 | 504 | 132 | 26.19 (22.40–30.26) | Ref |
| Bam H1C a | 7 | 598 | 179 | 29.93 (26.29–33.78) | 1.27 (0.83–1.93) |
| EBER2 | 3 | 141 | 50 | 35.46 (27.59–43.95) | 1.74 (1.06–2.86) |
| LMP1 | 3 | 127 | 7 | 5.51 (2.24–11.03) | 0.27 (0.12–0.59) |
| EBNA1 | 2 | 90 | 2 | 2.22 (0.27–7.71) | 0.29 (0.05–1.64) |
| BXLF1 | 1 | 95 | 44 | 46.32 (36.02–56.85) | 3.27 (1.79–5.98) |
| Pol | 1 | 92 | 19 | 20.65 (12.92–30.36) | 1.06 (0.55–2.05) |
| Gp220 | 1 | 57 | 13 | 22.81 (12.74–35.84) | 0.15 (0.01–1.76) |
| LMP2 | 1 | 55 | 1 | 1.82 (0.05–9.72) | 0.24 (0.03–2.18) |
| BZLF1 | 1 | 55 | 0 | 0 (0–6.49)c | 0 (P = 0.0416)d |
| EBNA4 | 1 | 48 | 5 | 10.42 (3.47–22.66) | 0.14 (0.04–0.47) |
| Raji | 1 | 45 | 0 | 0 (0–7.87)c | 0 (P = 0.0648)d |
| BALF5 | 1 | 45 | 0 | 0 (0–7.87)c | 0 (P = 0.0648)d |
| LF3 | 1 | 15 | 6 | 40.00 (16.34–67.71) | 2.53 (0.82–7.80) |
95% CI: confidence interval, OR: odds ratio.
a
: One study [10] was divided into six parts because samples from six different countries were tested. Three studies [11], [22], [30] were excluded because one [11] could not offer the EBV DNA prevalence detected by each primer, respectively, and the others [22], [30] only included 1 case.
b
: adjusted by normalizing the constituent ratio of region and DNA specimen of the Bam H1W group.
c
: one-sided, 97.5% confidence interval.
d
: exact confidence levels not possible with zero count cells.