Table 1. Subject Information.
Subject Index | Gestational age at birth (weeks+days) | Gestational age at recording (weeks+days) | Bipolar Montage | Remaining electrodes | Recording duration (hours) | Number of events per hour (mean±s.e.m) | Ultrasound details | Further details |
1 | 23+3 | 23+4 | 1 | All | 24.0 | 263.1±26.7 | N | Normal at 6 months. |
2 | 23+5 | 23+5 | 1 | 1–3,5,7,8 | 5.23 | 236.5±16.7 | N | Chronic lung disease. |
3 | 24+5 | 24+5 | 1 | All | 12.5 | 286.2±20.9 | N | Normal at 10 weeks. |
4 | 25+5 | 25+5 | 1 | All | 23.98 | 247.6±20.1 | N | Normal at 9 months. |
5 | 25+5 | 26+2 | 1 | All | 22.8 | 168.1±18.4* | A | Laser treatment for retinopathy, developed a left porencephalic cyst, chronic lung disease. |
6 | 24+1 | 27+3 | 2 | 1,5–7,9,10 | 18.48 | 85.4±14.3* | B | Head CT – left transparietal shunt in situ, dilation of lateral, 3rd and 4th ventricles. Porencephalic cyst secondary to germinal matrix haemorrhage. Retinopathy of prematurity, chronic lung disease. |
7 | 25+1 | 27+4 | 2 | 1,4,5,7,10 | 21.59 | 94.4±17.8* | C | Died from necrotizing enterocolitis. |
8 | 26+1 | 28+0 | 2 | 1–8,10 | 22.74 | 92.3±7.9* | D | Chronic lung disease. |
9 | 26+3 | 28+2 | 2 | All | 12.36 | 329.3±22.9 | N | Seen at 12 weeks post term, behaving normally for age. |
10 | 30+1 | 30+1 | 2 | 1,4,6–8,10 | 23.96 | 148.6±19.5 | N | Discharge at term, well. |
11 | 30+5 | 30+5 | 1 | 1,2,4–6,8 | 10.03 | 251.8±57.5 | N | Normal at 6 weeks old. |
1 Subject information. Ages are given as weeks+days. Two different bipolar montages were used. 1 = F4-C4, C4-O2, F3-C3, C3-O1, T4-C4, C4-Cz, Cz-C3, C3-T3, 2 = F4-C4, C4-P4, P4-O2, F3-C3, C3-P3, P3-O1, T4-C4, C4-Cz, Cz-C3, C3-T3. Remaining electrodes indicates those electrodes used for analysis after artefact rejection and removal of short (<1000) IEI sequences – see methods. Electrodes are numerically indexed corresponding to the list here. Number of events per hour is averaged across all (remaining) electrodes. Subjects with haemorrhages (*) had significantly lower number of events per hour – two sample t-test, P = 1.4×10−14. Ultrasound details are indicated by N = normal, A = intraventricular/parenchymal haemorrhage (grade 4) left hemisphere, intraventricular haemorrhage (grade 3) right hemisphere, B = left germinal matrix haemorrhage, grade 4, C = bilateral germinal matrix haemorrhage grade 1 and cystic changes in post ventricular white matter and D = bilateral intraventricular haemorrhage involving parenchyma on right, grade 3 left, grade 4 right. Further details provide known follow up details for each subject. One child (subject 7) died of non-neurological complications of prematurity.