Table 2. Hazard ratios for death (from any cause) among patients with NSCLC, according to multivariable Cox regression analysis*.
Variable | Hazard ratio (95% C.I.) | P |
LCRMP-1 | 26.22 (7.56 to 90.94) | <.0001 |
p-GSK3β | 0.48 (0.2 to 1.16) | 0.102 |
Sex | 2.48 (0.97 to 6.37) | 0.058 |
Histological type | 0.15 (0.04 to 0.52) | 0.003 |
Tumor stage | 0.47 (0.3 to 0.73) | 0.001 |
*Stepwise selection was used to choose the optimal multivariable Cox proportional hazard regression model. LCRMP-1 and phosphorylated GSK3β expression was designated as ‘high’ or ‘low’ using 50% and 70% cell positivity as the cut-off point respectively, and were adjusted by histological type (squamous cell carcinoma as the referent vs. adenocarcinoma), and stage (stage I as the referent vs. stage II vs. stage III). P values (two-sided) were calculated using a chi-square test. Abbreviations, LCRMP-1, long-form collapsin response mediator protein-1; p-GSK3β, phosphorylated Glycogen synthase kinase-3β; CI, confidence interval.