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. 2012 Feb 21;7(2):e31689. doi: 10.1371/journal.pone.0031689

Table 2. Hazard ratios for death (from any cause) among patients with NSCLC, according to multivariable Cox regression analysis*.

Variable Hazard ratio (95% C.I.) P
LCRMP-1 26.22 (7.56 to 90.94) <.0001
p-GSK3β 0.48 (0.2 to 1.16) 0.102
Sex 2.48 (0.97 to 6.37) 0.058
Histological type 0.15 (0.04 to 0.52) 0.003
Tumor stage 0.47 (0.3 to 0.73) 0.001

*Stepwise selection was used to choose the optimal multivariable Cox proportional hazard regression model. LCRMP-1 and phosphorylated GSK3β expression was designated as ‘high’ or ‘low’ using 50% and 70% cell positivity as the cut-off point respectively, and were adjusted by histological type (squamous cell carcinoma as the referent vs. adenocarcinoma), and stage (stage I as the referent vs. stage II vs. stage III). P values (two-sided) were calculated using a chi-square test. Abbreviations, LCRMP-1, long-form collapsin response mediator protein-1; p-GSK3β, phosphorylated Glycogen synthase kinase-3β; CI, confidence interval.