Table 1. Gene expression of metabolic genes in liver.
| C57Bl6 | alb-SREBP-1c | |
| FAS | 8.62±4.61 | 106.34±51.24** |
| SCD1 | 373.87±159.52 | 2017.10±159.37** |
| FADS1 | 45.54±8.18 | 119.12±27.88** |
| FADS2 | 20.98±7.09 | 82.78±18.89** |
| EVOL5 | 20.44±2.92 | 186.33±27.38** |
| EVOL6 | 0.06±0.02 | 1.09±0.41** |
| GPAT | 0.80±0.40 | 8.80±3.76** |
| HMG-CoAR | 1.28±0.53 | 16.19±2.49** |
| LDLR | 0.40±0.08 | 1.84±0.27** |
| ABCA1- | 0.43±0.04 | 2.06±0.48** |
| MTTP | 13.32±4.39 | 44.12±9.52** |
| GLUT2 | 15.46±3.30 | 4.36±2.10** |
| PEPCK | 4.06±2.46 | 32.78±16.63** |
| G6Pase | 0.92±0.12 | 0.97±0.09 |
| pyruvate kinase | 58.83±6.95 | 90.59±13.85** |
| malic enzyme | 0.01±0.002 | 0.02±0.001** |
Data are given as mean ± SD (n = 20, each genotype) in arbitrary units normalized to 18 S RNA contend. T-test C57Bl6 vs. alb-SREBP-1c: **p<0.01.
The hepatic expression level of genes was determined by RT-PCR (n = 20 each). The relative RNA amount shown in arbitrary units was calculated and plotted ± S.D. Students t-test was performed to determine significance (C57Bl6 vs. alb-SREBP-1c mice: **p<0.01).