Table 5. Physiological parameters and serum lipid composition.

	C57Bl6	alb-SREBP-1c
ALT [U/l]	31.45±13.72	61.76±23.94**
AST [U/l]	30.22±19.55	71.00±23.49**
cholesterol [mg/dl]	106.08±16.71	106.53±20.83
triglceride [mg/l]	124.23±33.17	221.76±40.67**
leptin [ng/ml]	15.81±5.71	55.40±5.91**
FFA serum [g/l]	0.90±0.1	2.42±0.19**
TFA liver [mg/g tissue]	24.17±5.39	37.47±9.89**
TFA fat [mg/g tissue]	748.03±34.46	819.93±33.50

Data are mean ± SD (n = 20). T-test C57Bl6 vs. alb-SREBP-1c: **p<0.01.

Clinical parameters were measured in C57Bl6 and alb-SREBP-1c mice (n = 20, for each). Triglycerides cholesterol, total protein and liver enzymes (ALT, AST) were determined on a Hitachie 912 laboratory automat. Students t-test was performed to determine significance (C57Bl6 vs. alb-SREBP-1c mice: **p<0.01).