Table 1. Calculated pharmacokinetic parameters of scopolamine in pig plasma after a 5-minute topical application of the drug.
| Parameter* | Units | Pig No. | ||||||
| Control group | Experimental group (Cnidocysts) Preparation | |||||||
| 1A | 2A | 3A | 4A | 5A | 6A | 7A | ||
| Cmax | pg/ml | 155 | 98.4 | 148.4 | 419.5 | 855.3 | 239.5 | 486.6 |
| Tmax | hours | 3.0 | 4.0 | 1.0 | 0.5 | 0.5 | 0.5 | 0.5 |
| t1/2 | hours | 4.4 | 6.8 | 9.7 | 5.2 | 5.6 | 4.8 | 7.1 |
| AUC0–24 | hours(pg/ml) | 1191.5 | 911.5 | 816.1 | 1973.0 | 2488.9 | 970.1 | 1155.3 |
| AUCINF | hours(pg/ml) | 1316.9 | 1028.7 | 946.5 | 2320.8 | 2628.7 | 1093.1 | 1289.9 |
*
Cmax, peak plasma concentration; Tmax, time to maximal concentration; t½, half-life elimination time; AUC, Area under the plasma concentration time curve.