Table 2.
Drug susceptibility tests of mycobacterial strains
| MIC (µg ml−1) | |||||
|---|---|---|---|---|---|
| Strain | Description | INH | ETH | EMB | RIF |
| mc2155 | M. smegmatis mc2155 | 5 | 10 | 0.5 | 10 |
| mc2155 pMV261 | mc2155 transformed with pMV261 | 5 | 10 | 0.5 | 10 |
| mc2155 pMV261::nudCRv | mc2155 transformed with pMV261-NudCRv | 5 | 10 | 0.5 | 10 |
| mc2155 pMV261::nudCBCG | mc2155 transformed with pMV261-NudCBCG | > 200 | 200 | 0.5 | 10 |
| mc2155 ΔnudC | mc2155 knockout nudC | 1 | 0.5 | 0.5 | 10 |
| mc2155 pMV261::nudCSm | mc2155 transformed with pMV261-NudCSm | 200 | 50 | 0.5 | 10 |
| BCG | M. bovis BCG Pasteur1173P2 | 0.1 | 5 | 2.5 | 0.1 |
| BCG pMV261 | BCG transformed with pMV261 | 0.1 | 5 | 2.5 | 0.1 |
| BCG pMV261::nudCRv | BCG transformed with pMV261-NudCRv | 0.1 | 5 | 2.5 | 0.1 |
| BCG pMV261::nudCBCG | BCG transformed with pMV261-NudCBCG | > 2 | > 50 | 2.5 | 0.1 |
| BCG ΔnudC | BCG knockout nudC | 0.05 | 1 | 2.5 | 0.1 |
| H37Ra | M. tuberculosis H37Ra | 0.1 | 1 | 2.5 | 0.01 |
| H37Ra ΔnudC | H37Ra knockout nudC | 0.1 | 1 | 2.5 | 0.01 |
| mc2155 ΔnudC pMV261::nudCSm | mc2155 ΔnudC transformed with pMV261-NudCSm | > 200 | 200 | 0.5 | 10 |
| BCG ΔnudC pMV261::nudCBCG | BCG ΔnudC transformed with pMV261-NudCBCG | > 2 | > 50 | 2.5 | 0.1 |