Figure 5.

Lag-time dependence of the local MSD exponent $\langle \alpha \rangle$ (a) and the mean effective diffusion coefficient $\langle D\rangle$ (b) in various cytoskeleton states: WT cells (experiments as black circles, simulations as black line), Benomyl-assisted MT depolymerization (exp: blue triangles, sim: blue line), Latrunculin A-assisted F-actin depolymerization (green squares, green line), simultaneous MT and F-actin depolymerization (red diamonds, red line), and as reference NP diffusion in glycerol (yellow triangles, yellow line) for both experimental data (symbols) and simulations (solid lines). Data shown in Fig. 4a correspond to a lag time of 0.735 s (vertical dashed line).