Table 2.
m-values
| m (kBT M−1) | mcorr (kBT M−1) | mMD (kBT M−1) | |
|---|---|---|---|
| KF | −0.35(0.02) | −0.32(0.02) | −0.30(0.06) |
| KCl | −0.38(0.02) | −0.38(0.02) | −0.14(0.07) |
| NaCl | −0.38(0.02) | −0.42(0.02) | −0.78(0.07) |
| GdmCl | −0.44(0.04) | −0.51(0.04) | −0.97(0.09) |
| NaClO4 | −0.79(0.08) | −0.97(0.08) | −1.27(0.09) |
The m-value is determined using Eq. 1 in the Supporting Material, the MD-derived Δ(ASA)i for the EK-peptide and reported values for partial mi-values per unit ASA for polar “p”, nonpolar “np”, and ester oxygen “eo” compounds (see Table S1 and (8,16)). mcorr is the corrected value including the contribution of the salt bridge (see Supporting Material). mMD is the m-value derived from MD simulations including salt. Errors are shown in parenthesis (see Methods in the Supporting Material).