Table 1.
Markers and nuclei in the wild type and Gli3Xt/Xt and Gli2zfd/zfd thalamus.
Gli3Xt/Xt | Gli2zfd/zfd | n-Shh/Gli3 | ||
---|---|---|---|---|
CENTRAL | ||||
ATN | Lhx2 | −−− | ++ | −−− |
Cdh6 | ++ | ++ | −−− | |
VP | Cdh6 | ++ | + | −−− |
VM | Ngn2 | −−− | + | −−− |
Dorsal | Calb2 | ++ | −−− | −−− |
Cdh6 | −−− | + | −−− | |
LGN | Ngn2 | −−− | + | −−− |
Cdh6 | ++ | −−− | −−− | |
MGN | Calb2 | ++ | −−− | −−− |
Gbx2 | −−− | + | −−− | |
Lhx2 | −−− | + | −−− | |
Medial | Calb2 | + | +++ | ++++ |
Gbx2 | + | +++ | ++++ | |
Lhx2 | + | +++ | ++++ |
The symbol “+++” denotes normal expression; “++” and “+” denote reduced and very reduced intensity of expression, respectively; “++++” denotes expression more intense or over a larger area than in the wild type; and “−−−” denotes loss of expression.