TABLE 2.

Heart gene expression in Dgat1 and Dgat1 mice (n = 5–6)

	Chow Diet			High-Fat Diet
Gene	WT	Dgat1/−	Dgat1−/−	WT	Dgat1	Dgat1−/−
	%	%	%	%	%	%
Ppara	100 ± 37	89 ± 35	38 ± 17a	175 ± 41a	122 ± 41	111 ± 22c
Ppard	100 ± 20	76 ± 26	44 ± 21a	124 ± 47	131 ± 58	69 ± 13c
Pparg	100 ± 31	88 ± 17	28 ± 11b	244 ± 69b	147 ± 40	124 ± 38c
Cd36	100 ± 28	82 ± 49	43 ± 21a	307 ± 113b	153 ± 46a	12 ± 33d
Lpl	100 ± 55	47 ± 15	34 ± 14a	78 ± 32	118 ± 41	52 ± 30
Atgl	100 ± 47	66 ± 26	34 ± 17a	185 ± 54a	135 ± 38	71 ± 21c
Pdk4	100 ± 53	62 ± 34	30 ± 12a	345 ± 127b	242 ± 84a	88 ± 35d
Aox	100 ± 17	86 ± 31	67 ± 27a	211 ± 77b	155 ± 57	97 ± 33c
Cptlb	100 ± 25	88 ± 23	63 ± 19a	241 ± 65b	147 ± 26a	105 ± 42c
PGCla	100 ± 46	127 ± 26	148 ± 39	57 ± 11a	73 ± 31	114 ± 35c
Glut1	100 ± 34	151 ± 56	215 ± 45a	123 ± 28	159 ± 47	187 ± 39c
Glut4	100 ± 30	274 ± 53b	479 ± 133b	83 ± 23	129 ± 42	260 ± 58d

AOX, acylCoA oxidase; ATGL, adipose TG lipase; CPT, carnitine palmitoyl transferase; DGAT, diacylglycerol acyl transferase; GLUT, glucose transporter; PDK, pyruvate dehydrogenase kinase; PGC, proliferator-activated receptor gamma coactivator; PPAR, peroxisome proliferator-activated receptor; WT, wild type.

^aP < 0.05 versus chow diet WT.

^bP < 0.01 versus chow diet WT.

^cP < 0.05 versus high-fat diet WT.

^dP < 0.01 versus high-fat diet WT.