Table 3.
Heart rate variability measures in patients with multiple system atrophy (MSA) and age-matched controls.
| MSA (n = 12) | Age-matched control (n = 69) | P value | Bootstrap samples of age-matched control (n = 12) | |
|---|---|---|---|---|
| Mean NN, ms | 766 ± 89 | 775 ± 110 | 0.745 | 776 (723–832) |
| SDNN, ms | 59.7 ± 23.0 | 90.4 ± 28.6 | <0.001 | 89.0 (75.4–104.2) |
| SDANN, ms | 19.9 ± 6.5 | 47.5 ± 28.7 | <0.001 | 48.8 (35.5–64.5) |
| RMSSD, ms | 13.6 ± 4.4 | 22.5 ± 11.4 | <0.001 | 21.6 (16.3–27.6) |
| ln HF, ln ms2 | 3.75 ± 0.90 | 4.97 ± 1.08 | <0.001 | 4.93 (4.34–5.50) |
| ln LF, ln ms2 | 4.02 ± 0.90 | 5.90 ± 0.97 | <0.001 | 5.90 (5.39–6.36) |
| ln VLF, ln ms2 | 5.92 ± 0.84 | 7.26 ± 0.81 | <0.001 | 7.30 (6.89–7.72) |
| ln ULF, ln ms2 | 7.78 ± 0.93 | 8.47 ± 0.64 | 0.029 | 8.45 (8.14–8.79) |
| LF/HF ratio | 1.69 ± 1.24 | 3.28 ± 2.49 | 0.002 | 3.47 (2.25–4.87) |
| DC, ms | 3.38 ± 0.98 | 6.23 ± 1.59 | <0.001 | 5.82 (5.11–6.53) |
| AC, ms | −3.38 ± 0.93 | −6.51 ± 1.77 | <0.001 | −6.13 (−6.94 to −5.28) |
| α1 | 0.86 ± 0.24 | 1.17 ± 0.15 | <0.001 | 1.21 (1.08–1.33) |
| α2 | 1.23 ± 0.09 | 1.18 ± 0.04 | 0.118 | 1.19 (1.15–1.23) |
| λ25s | 0.46 ± 0.07 | 0.39 ± 0.07 | 0.005 | 0.38 (0.35–0.43) |
| λ2-slope | −0.05 ± 0.12 | −0.01 ± 0.08 | 0.309 | 0.00 (−0.04 to 0.04) |
Fifth column shows mean value and 95%-confidence interval based on 2000 bootstrap samples. P< 0.05.