Table 1. Tumor characteristics and clinical variables: association with nestin expression And with overall survival.
N. of patients | Nestin | P* | N. of events | P° | |
---|---|---|---|---|---|
Age | 0.276 | 0.541 | |||
≤51# | 25 | 11 | 15 | ||
>51 | 28 | 17 | 15 | ||
Tumor stage | 0.016 | 0.455 | |||
T4abc | 38 | 16 | 21 | ||
T4d | 15 | 12 | 9 | ||
Axillary nodes§ | 1.000 | 0.029 | |||
CLN 0 | 12 | 6 | 3 | ||
CLN + | 41 | 22 | 27 | ||
Triple negative | 0.002 | 0.039 | |||
Yes | 18 | 15 | 13 | ||
No | 35 | 13 | 17 | ||
Hormone receptor status | 0.029 | 0.140 | |||
ER − PR− | 24 | 17 | 16 | ||
ER − PR + | 1 | 1 | 0 | ||
ER + PR − | 12 | 6 | 6 | ||
ER + PR + | 16 | 4 | 8 | ||
Estrogen receptor status | 0.013 | 0.075 | |||
ER+ | 28 | 10 | 14 | ||
ER − | 25 | 18 | 16 | ||
Progesteron receptor status | 0.037 | 0.079 | |||
PR + | 17 | 5 | 8 | ||
PR − | 36 | 23 | 22 | ||
HER2 status | 0.162 | 0.635 | |||
HER2 + | 10 | 3 | 5 | ||
HER2 − | 43 | 25 | 25 | ||
Grading | 0.360 | 0.461 | |||
G2 | 38 | 22 | 23 | ||
G3 | 15 | 6 | 7 | ||
Pathological response | 0.255 | 0.087 | |||
pCR | 8 | 5 | 2 | ||
<pCR | 45 | 23 | 28 | ||
Clinical response | 0.256 | 0.043 | |||
Complete response | 8 | 4 | 2 | ||
Partial response | 36 | 17 | 20 | ||
< Partial response | 9 | 7 | 8 |
Fisher's exact test or Pearson's test;
log-rank test;
median age;
after primary chemotherapy.