Figure 7.
Efficacy against sporozoite challenge in mice immunized with MVA at separate sites. BALB/c mice that had been immunized with MVA at separate sites were challenged i.v. with 1000 sporozoites fourteen days after MVA. (A) Parasitemia on day 5 post-challenge. Bars represent geometric mean parasitemia. (B) Parasitemia over time for the different vaccine groups. Lines indicate percentage of infected RBC for individual mice of six per group. Crosses indicate mice that were culled. *** P ≤ 0.001