Table 1.

Passive, active, and synaptic membrane properties of mouse airway ganglionic neurons

	Phasic Neurons	Tonic Neurons
Resting potential	−48 ± 3 mV	−51 ± 4 mV
Input resistance	44 ± 5 MΩ	69 ± 8 MΩ*
Time constant	5.3 ± 0.4 ms	6.9 ± 0.8 ms*
Input capacitance	6.9 ± 0.5 pF	9.2 ± 0.8 pF*
Single action potential
Amplitude	46 ± 10 mV	55 ± 12 mV
Duration	7.4 ± 0.1 ms	6.0 ± 0.3 ms*
AHP amplitude	8.0 ± 1 mV	5.9 ± 1 mV
AHP duration	70 ± 13 ms	40 ± 9 ms*
AHP amplitude	15 ± 4 mV	7 ± 3 mV*
Four action potentials
AHP amplitude2	8.9 ± 3 mV	7.2 ± 3 mV
AHP Duration	279 ± 24 ms	135 ± 34 ms*
Synaptic potentials3
Amplitude	16.3 ± 3 mV (13–19 mV)
Duration	7.8 ± 2 ms (5.8–10.1 ms)
Threshold	12 ± 4 mV (10–18 mV)
No. Populations	1 ± 0

All values are means ± SE for 51 phasic and 31 tonic neurons. Eight neurons had a tonic response in only 1 of 4 steps and were included as tonic neurons in the table results. AHP amplitude following 4 consecutive action potentials was measured at the 4th action potential; duration from the end of the 4th action potential until the potential returned to the prestimulus resting potential.

^*P < 0.05 compared with phasic neurons. Vagus nerve-stimulated synaptic potentials were measured in 12 phasic and 9 tonic neurons; thus far, all fEPSP parameters are similar for both cell types. For fEPSP recordings, QX314 (3 μM) was added to the recording electrode electrolyte. AHP, afterhyperpolarization; fEPSP, fast excitatory postsynaptic potential.