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. 2011 Dec 19;42(1):119. doi: 10.1186/1297-9716-42-119

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Copyright ©2011 Hart et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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CD8 T cell clones specific for the Tp1 antigen show MHC class I-restricted cytotoxicity. Two Tp1 specific CD8 T cell clones were tested in a 4-hour ¹¹¹Indium release cytotoxicity assay against autologous (solid black symbols) and MHC mis-matched (open symbols) Tp1_214-224-pulsed targets at defined effector:target ratios.