Table 1.
CD81- cells (%) | |||||
---|---|---|---|---|---|
sh populations | ntshRNA | 5.8 | |||
shCD81 8 | 20.4 | ||||
shCD81 9 | 88.4 | ||||
shCD81 10 | 92.8 | ||||
shCD81 11 | 10.0 | ||||
shCD81 12 | 31.0 | ||||
shCD81 9+10+12 | 98.5 | ||||
CD81- cells (%) | Specific cell growth (h-1) | IC50 (µM tert-butyl hydroperoxide) | Specific RT productivity (10-6 ng/cell.h) | ||
293 rVLP | 2.1 | 0.0201 ± 0.0002 | 3.3 ± 1.1 | 1.7 ± 0.3 | |
ntshRNA | 0.8 | 0.020 ± 0.002 | 9.2 ± 1.4 | 2.3 ± 0.4 | |
shCD81 9+10+12 clones | shCD81 #9 | 86.4 | 0.0124 ± 0.0004 | 15.4 ± 1.0 | 0.9 ± 0.2 |
shCD81 #14 | 97.1 | 0.021 ± 0.002 | 4.5 ± 1.1 | 2.0 ± 0.4 | |
shCD81 #19 | 92.9 | 0.015 ± 0.001 | 6.5 ± 1.1 | 1.2 ± 0.2 | |
shCD81 #22 | 88.9 | 0.018 ± 0.001 | 6.0 ± 1.1 | 1.8 ± 0.4 | |
shCD81 #30 | 82.3 | 0.017 ± 0.001 | 5.6 ±1.0 | 1.4 ± 0.2 |