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. 2011 Nov 22;5(Suppl 8):P72. doi: 10.1186/1753-6561-5-S8-P72

Table 1.

CD81 down-regulation in 293rVLP cells

CD81- cells (%)
sh populations ntshRNA 5.8
shCD81 8 20.4
shCD81 9 88.4
shCD81 10 92.8
shCD81 11 10.0
shCD81 12 31.0
shCD81 9+10+12 98.5

CD81- cells (%) Specific cell growth (h-1) IC50 (µM tert-butyl hydroperoxide) Specific RT productivity (10-6 ng/cell.h)

293 rVLP 2.1 0.0201 ± 0.0002 3.3 ± 1.1 1.7 ± 0.3
ntshRNA 0.8 0.020 ± 0.002 9.2 ± 1.4 2.3 ± 0.4
shCD81 9+10+12 clones shCD81 #9 86.4 0.0124 ± 0.0004 15.4 ± 1.0 0.9 ± 0.2
shCD81 #14 97.1 0.021 ± 0.002 4.5 ± 1.1 2.0 ± 0.4
shCD81 #19 92.9 0.015 ± 0.001 6.5 ± 1.1 1.2 ± 0.2
shCD81 #22 88.9 0.018 ± 0.001 6.0 ± 1.1 1.8 ± 0.4
shCD81 #30 82.3 0.017 ± 0.001 5.6 ±1.0 1.4 ± 0.2