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. 2012 Jan 19;5:2. doi: 10.1186/1757-2215-5-2

Table 2.

Top ten genes differentially expressed (D/U) during early differentiation of mES and mEC cells.

Gene Symbol GeneName Fold Change
SCC-PSA1
Upregulated
Olfr1450 Olfactory receptor 1450 9.0
Fgf5 Fibroblast growth factor 5 8.9
Dscam Down syndrome cell adhesion molecule 7.7
Afp Alpha fetoprotein 5.2
Rbp4 Retinol binding protein 4, plasma 5.0
Slc28a2 Solute carrier family 28, member 2 4.5
Bid3 BH3 interacting domain, apoptosis agonist 4.3
Igfbp5 Insulin-like growth factor binding protein 5 4.2
Irs4 Insulin receptor substrate 4 3.8
Downregulated
Clec2d C-type lectin domain family 2, member d -11.3
Fbln5 Fibulin 5 -6.5
Cav2 Caveolin 2 -5.6
Irf5 Interferon regulatory factor 5 -5.5
Lsp1 Lymphocyte specific 1 -5.1
Olfr787 Olfactory receptor 787 -4.9
Fxyd4 FXYD-containing ion transport regulator 4 -4.8
Nupr1 Nuclear protein 1 -4.7
Kcnk4 K channel, subfamily K, member 4 -4.6
Cpne2 Copine II -4.6
Nulli-SCC
Upregulated
Flt1 FMS-like tyrosine kinase 1 5.3
Npy5r Neuropeptide Y receptor Y5 5.0
Olfr786 Olfactory receptor 786 4.4
Fau FBR-MuSV ubiquitously expressed 4.1
Gm392 Gene model 392, (NCBI) 3.7
Gm449 Gene model 449, (NCBI) 3.2
Loxl2 Lysyl oxidase-like 2 2.9
Aoc3 Amine oxidase, copper containing 3 2.8
Serpini2 Serine proteinase inhibitor 1 2.8
Olfr870 Olfactory receptor 870 2.7
Downregulated
Ssa2 Sjogren syndrome antigen A2 -5.3
4930486G11Rik RIKEN cDNA 4930486G11 gene -4.6
1700052K11Rik RIKEN cDNA 1700052K11 gene -4.5
Refbp2 RNA and export factor binding protein 2 -4.4
2900011O08Rik RIKEN cDNA 2900011O08 gene -3.7
Tmem62 Transmembrane protein 62 -3.7
Tirap TIR domain-containing adaptor protein -3.6
Defb13 Defensin beta 13 -3.5
Es31 Esterase 31 -3.4
Nap1l5 Nucleosome assembly protein 1-like 5 -3.3
mES
Upregulated
H1foo H1 histone family, member O, oocyte-specific 64.2
Mrgprh MAS-related GPR, member H 60.8
Mak10 MAK10 homolog 59.6
V1rd11 Vomeronasal 1 receptor, D11 57.8
B230317F23Rik RIKEN cDNA B230317F23 gene 41.1
Gdpd3 Glycerophosphodi- phosphodiesterase 3 39.2
Na Gene model 979, (NCBI) 32.3
Eif2c4 Euk translation initiation factor 2C, 4 30.6
Tll1 Tolloid-like 22.9
Na Similar to Ig gamma-2a chain precursor 20.1
Downregulated
MP4 Proline rich protein MP4 -70
Pck1 Phosphoenolpyruvate carboxykinase 1 -49.3
Fgfrl1 Fibroblast growth factor receptor-like 1 -38.3
Rpgrip1l Rpgrip1-like -20.6
Olfr508 Olfactory receptor 508 -16.0
Eif5a2 Euk translation initiation factor 5A2 -15.6
9130015A21Rik RIKEN cDNA 9130015A21 gene -14.6
Tecta Tectorin alpha -11.0
Fancc Fanconi anemia, complementation group C -10.7
Pax9 Paired box gene 9 -9.9