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. 2011 Nov 7;590(Pt 2):259–272. doi: 10.1113/jphysiol.2011.209577

Figure 5. Current reversal potentials are independent of [Cl−] and obey the Nernst equation for [SCN−].

Figure 5

A, reversal potentials from cells expressing SLC26A5 (RAT)/prestin or Slc26a5 (DANRE)/prestin at different internal SCN− concentrations. Symbols are means ± SEM from 5 or more experiments, whereas continuous and dashed lines provide predictions for different Cl−/SCN− exchange stoichiometries or SCN− diffusion potentials calculated using eqns (3) and (4), respectively. The external solution contained 5 mm SCN− and 149 mm Cl−. B, reversal potentials from cells expressing SLC26A5 (RAT)/prestin or Slc26a5 (DANRE)/prestin at varying external [Cl−] and [SCN−]i/[SCN−]o= 30/5 versus external [Cl−]. Means ± SEM from 5 or more cells. The Nernst potential for SCN− is +45 mV.