Table 2.
Main and co-agents, main agents separated by sex
| Toxic agent | Main+co-agents | Main agents | |||
|---|---|---|---|---|---|
| n (%) | Total n (%) | Males n (%) | Females n (%) | p-value | |
| Ethanol | 1236 (53) | 1018 (43) | 688 (44) | 330 (42) | ns |
| Opioids | 613 (26) | 519 (22) | 415 (27) | 104 (13) | < 0.001* |
| CO/fire smoke | 233 (10) | 231 (10) | 136 (9) | 95 (12) | 0.018* |
| Benzodiazepines | 376 (16) | 122 (5) | 72 (5) | 50 (6) | ns |
| Amphetamines | 196 (8) | 73 (3) | 63 (4) | 10 (1) | < 0.001* |
| Paracetamol | 104 (4) | 58 (2) | 17 (1) | 41 (5) | < 0.001* |
| GHB | 58 (2) | 54 (2) | 39 (3) | 15 (2) | ns |
| Antidepressants | 54 (2) | 39 (2) | 10 (1) | 29 (4) | < 0.001* |
| Scopolamine | 45 (2) | 34 (1) | 26 (2) | 8 (1) | ns |
| Neuroleptics | 42 (2) | 29 (1) | 7 (< 0.5) | 22 (3) | < 0.001* |
| Zopiclone/zolpidem | 65 (3) | 27 (1) | 11 (1) | 16 (2) | 0.011* |
| Cocaine | 32 (1) | 12 (1) | 10 (1) | 2 (< 0.5) | ns |
| NSAIDs | 31 (1) | 12 (1) | 6 (< 0.5) | 6 (1) | ns |
| Antihistamines | 24 (1) | 10 (< 0.5) | 2 (< 0.5) | 8 (1) | 0.004* |
| Antiepileptics | 16 (1) | 9 (< 0.5) | 3 (< 0.5) | 6 (1) | ns |
| Ecstasy | 14 (1) | 5 (< 0.5) | 3 (< 0.5) | 2 (< 0.5) | ns |
| Other gases | 21 (1) | 20 (1) | 12 (1) | 8 (1) | ns |
| Other | 194 (8) | 76 (3) | 33 (2) | 43 (5) | < 0.001* |
| Total cases | 2348 (100) | 1553 (100) | 795 (100) | ||
*Significant
Main agents present in ≤ 5 patients were defined as "other"
NSAIDs: non-steroidal anti-inflammatory drugs
Among the opioids as main agent, 478 were by illegal substances. Among the legal opioids, 19 were by methadone and 14 were by buprenorphine. Among the cases involving antidepressants as the main agent, 22 were by selective serotonin reuptake inhibitors and five were by tricyclic antidepressants. Among the cases involving paracetamol as the main agent, 21 were by codeine-combination formulas