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. 2012 Jan 4;134(3):1454–1457. doi: 10.1021/ja210496n

Figure 3.

Figure 3

Competitive binding of Zn and OCT to BSA studied by ITC. (A) Zn binding to BSA (25 μM) in the presence and absence of 5 molar equiv of OCT. (B) OCT binding to BSA and Zn1BSA. Open circles with blue fits correspond to binary systems and filled circles with red fits to ternary systems. In each case, 34 injections of 8 μL of 333 μM ligand (Zn or OCT) were delivered over 16 s with 240 s between injections for complete equilibration.