Table 2. Association of AVPR1A and SLC6A4 SNPs, and 5 -HTTLPR, with singer/non-musician status.

Gene/polymorphism	Location (basepairs)	Individual alleles (minor/major)	Minor allele frequency in choral singers (n = 261)	Minor allele frequency in non-musicians (n = 258)	Odds ratio (95% CI)	P value
AVPR1A
rs1042615	63544209	A/G	0.42	0.42	1.01 (0.79–1.29)	0.93
rs10877969	63547239	C/T	0.14	0.14	1.05 (0.74–1.50)	0.78
rs11174811	63540476	A/C	0.14	0.15	0.94 (0.67–1.33)	0.73
SLC6A4
5-HTTLPR	28564498+	(La+Lg)/(Sa+Sg)*	0.42	0.40	1.10 (0.83–1.45)	0.50
rs2020933	28561755	T/A	0.05	0.06	0.81 (0.47–1.41)	0.46
rs2066713	28551665	A/G	0.37	0.42	0.81 (0.63–1.04)	0.09
rs2020939	28550732	A/G	0.44	0.39	1.24 (0.97–1.59)	0.08
rs8076005	28547210	G/A	0.20	0.20	1.02 (0.75–1.39)	0.89
rs2020942	28546914	T/C	0.37	0.42	0.81 (0.63–1.04)	0.11
rs140700	28543389	T/C	0.10	0.10	1.02 (0.69–1.53)	0.90
rs4583306	28538715	G/A	0.42	0.38	1.18 (0.92–1.51)	0.19
rs140701	28538532	T/C	0.42	0.38	1.19 (0.93–1.52)	0.17
rs4325622	28526475	C/T	0.47	0.43	1.15 (0.90–1.47)	0.25
rs3813034	28524804	C/A	0.46	0.43	1.14 (0.90–1.46)	0.28

*At 5-HTTLPR long alleles La and Lg have been combined, as have short alleles Sa and Sg, to permit analysis as a bi-allelic marker.