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. 2012 Feb 22;7(2):e31951. doi: 10.1371/journal.pone.0031951

Figure 3. Quantification of histamine by triple quadrupole mass spectrometry.

Figure 3

Histamine in HILIC-HPLC fractions B2–B7 from L. reuteri 6475 grown in a glucose-containing medium was quantified by triple quadrupole mass spectrometry. The y-axis indicates TNF production from activated human monocytoid cells. The concentration of histamine (pg/µL) is indicated above each bar graph. Elevated levels of histamine correlated with TNF inhibition.