Table 4. Times of origin (in years before 2008) for selected clades in the phylogenetic tree of Tick-borne encephalitis virus, obtained from the BEAST inference 4 based on a large E-sequences dataset.

Clade	Node in Figure 5b	tMRCA (median)	95% HPD
S-TBEV	A	825	631–1053
FE-TBEV	B	679	505–862
Neudoerfl – Scharl	C	218	150–289
Neudoerfl – Hypra	m	282	228–342
LIV369/T2 - LI/G	D	198	143 to 263
SSEV - LIVb	M	1116	896–1380
W-TBEV	E	334	243–442
LIV	F	870	676–1087
W-TBEV - SSEV - LIV	G	2027	1563–2565
W-TBEV - SSEV – LIV – TSEV - GGEV	H	2426	1841–3065

^{a b}correspond to the upper bonds of the divergence times respectively for the minor and major parent identified in figure 3.