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. 2012 Feb 22;7(2):e32091. doi: 10.1371/journal.pone.0032091

Table 2. SNPs with psychiatric illness associations and their location relative to the most proximal clock gene.

Gene Illness Association SNP Position Relative to Gene
PER1 SCZ rs3027232 Coding region of adjacent gene ALOXE3
NR1D2 SCZ rs2001209 High density gene area ∼20 kb from NR1D2, intronic in adjacent gene RPL15
RORA ADHDSCZ rs922781rs1351546 intronic in RORAintronic in RORA
RORB BD rs10869435 intronic in RORB
RORC SCZ rs868866 intronic in TDRKH ∼20 kb downstream from RORC
DEC1 MDDBDSCZBD 4 SNPsrs1537720rs11794627rs10982664 Intronic DEC1DEC1 promoter, enriched chromatinIntronic DEC1Intronic DEC1
NPAS2 ADHD rs11674199 Intronic NPAS2
ARNTL BD rs747601 ∼20 kb upstream promoter region
ARNTL2 ADHD rs11049004 Intronic in ARNTL2

The SNPs proximal to PER1 and RORC were determined to lie outside of these genes. The SNP proximal to NR1D2 was indeterminate. The remaining SNPs were determined to be located with the corresponding clock gene.