Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Menstrual blood loss
Systematic review	126 premenopausal women Data from 1 RCT	Amenorrhoea 1 year 3/43 (8%) with thermal balloon ablation 36/83 (43%) with bipolar radiofrequency ablation	Reported as significant P value not reported	Effect size not calculated	bipolar radiofrequency ablation
RCT	160 premenopausal women	Amenorrhoea 1 year 17/71 (24%) with hydrothermablation 35/75 (47%) with bipolar radiofrequency ablation	RR 2.0 95% CI 1.2 to 3.1	Moderate effect size	bipolar radiofrequency ablation
RCT	81 premenopausal women	Amenorrhoea 1 year 6/26 (23%) with thermal balloon ablation 14/25 (56%) with bipolar radiofrequency ablation	RR 2.4 95% CI 1.1 to 5.3	Moderate effect size	bipolar radiofrequency ablation
RCT	250 premenopausal women	Amenorrhoea 1 year 46/124 (37%) with thermal balloon ablation 42/126 (33%) with thermal balloon ablation plus post-procedural curettage	P = 0.53		Not significant