Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse drug effects
Systematic review	705 women 3 RCTs in this analysis	Withdrawal because of adverse effects 1/566 (1%) with gonadorelin analogues (goserelin or decapeptyl) 11/139 (8%) with danazol	RR 44.80 95% CI 5.83 to 344.00	Large effect size	gonadorelin analogues
Systematic review	340 women 3 RCTs in this analysis	Adverse effects with gonadorelin analogues (goserelin or decapeptyl) with danazol