Table 6.
Factors Associated With Incident Vaginal Intraepithelial Neoplasia in Multivariable Analysis
Characteristic | Hazard Ratio | Lower 95% Confidence Limit* | Upper 95% Confidence Limit | P | |
---|---|---|---|---|---|
CD4 count (per μl) | HIV seronegative (ref) | 1 | <.0001† | ||
Greater than 500 | 5.90 | 1.73 | 20.08 | 0.005 | |
200–500 | 14.48 | 4.52 | 46.43 | <.0001 | |
Less than 200 | 22.50 | 6.89 | 73.49 | <.0001 | |
Age (years) | Less than or equal to 34 (ref) | 1 | |||
35–39 | 0.83 | 0.46 | 1.48 | 0.53 | |
40–44 | 0.76 | 0.41 | 1.39 | 0.37 | |
Greater than or equal to 45 | 1.09 | 0.62 | 1.94 | 0.76 | |
Ethnicity | Black (ref) | 1 | |||
Hispanic | 0.65 | 0.39 | 1.06 | 0.08 | |
Other | 0.64 | 0.36 | 1.13 | 0.12 | |
Smoking | Never (ref) | 1 | |||
Former | 1.33 | 0.72 | 2.47 | 0.36 | |
Current | 1.90 | 1.13 | 3.21 | 0.02 | |
No. of sexual partner in past 6 months | 0 (ref) | 1 | |||
1 | 0.91 | 0.60 | 1.37 | 0.64 | |
2 or more | 0.71 | 0.34 | 1.50 | 0.37 | |
Parity | 0 (ref) | 1 | |||
1 | 0.86 | 0.50 | 1.46 | 0.57 | |
2 | 0.39 | 0.20 | 0.74 | 0.004 | |
Greater than or equal to 3 | 0.64 | 0.38 | 1.05 | 0.08 |
Confidence limit
P for trend