TABLE 1.
Baseline Participant Characteristics in the Cardiovascular Health Study and the Health ABC Study
| Characteristic | Cardiovascular Health Study (n=5335)
|
Health ABC Study (n=2935)
|
||
|---|---|---|---|---|
| Mean (SD) | Range | Mean (SD) | Range | |
| Age, years | 72.7 (5.5) | 65, 100 | 73.6 (2.9) | 68, 80 |
| Males, % | 42.4 | 47.9 | ||
| Race | ||||
| White, % | 84.7 | 58.6 | ||
| Black, % | 14.7 | 41.4 | ||
| Other, % | 0.6 | - | ||
| Body mass index, kg/m2 | 26.6 (4.5) | 14.7, 45.8 | 27.3 (4.8) | 14.6, 47.5 |
| Systolic blood pressure, mmHg | 136 (21) | 79, 227 | 136 (21) | 77, 224 |
| Diastolic blood pressure, mmHg | 71 (11) | 40, 116 | 71 (12) | 30, 120 |
| Heart rate, beats/minute | 65 (11) | 30, 113 | 65 (11) | 38, 113 |
| Hypertension, % | 46.3 | 43.4 | ||
| Diabetes, % | 11.2 | 14.8 | ||
| Smoking status | ||||
| Current, % | 11.8 | 10.5 | ||
| Past, % | 41.7 | 45.0 | ||
| Coronary heart disease | ||||
| Definite, % | 15.5 | 16.5 | ||
| Probable, % | 1.7 | 3.1 | ||
| Peripheral vascular disease, % | 2.1 | 4.7 | ||
| Cerebrovascular disease, % | 6.8 | 6.8 | ||
| Left ventricular hypertrophy, % | 4.4 | 11.9 | ||
| Atrial fibrillation, % | 2.1 | 1.4 | ||
| Hematocrit, % units | 41.8 (3.8) | 25.3, 56.7 | -† | |
| White blood count, 103/mm3 | 6.2 (1.6) | 1.3, 13.4 | -† | |
| Platelet count, 103/mm3 | 249 (69) | 48, 543 | -† | |
| Fasting glucose, mg/dl* | 101 (94, 111) | 53, 448 | 94 (87, 105) | 47, 449 |
| Creatinine, mg/dl | 1.05 (0.30) | 0.4,10.0 | 1.05 (0.41) | 0.5, 10.6 |
| Uric acid, mg/dl | 5.7 (1.5) | 0.5, 12.2 | -† | |
| Albumin, gm/dl | 4.00 (0.29) | 2.8, 5.2 | 3.98 (0.31) | 2.8, 5.0 |
| Total cholesterol, mg/dl | 212 (39) | 59, 370 | 203 (38) | 76, 372 |
| High density lipoprotein, mg/dl | 54 (15) | 18, 123 | 54 (17) | 13, 124 |
| Low density lipoprotein, mg/dl | 130 (35) | 25, 277 | 122 (35) | 6, 270 |
| Triglycerides, mg/dl* | 120 (92, 164) | 24, 710 | 118 (88, 162) | 26, 871 |
| Left ventricular ejection fraction, % normal/borderline/abnormal‡ | 92.4/5.0/2.6 | -† | ||
Values for continuous measures represent mean (SD) unless otherwise stated.
*
Expressed as median (25th, 75th percentile) because of skewed distributions.
†
Not available at baseline in Health ABC.
‡
Echocardiograms at baseline in CHS were available in 4720 of the 5335 (88.5%) participants in the validation cohort; no echocardiographic data at baseline were available in the Health ABC Study.