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Sennoside B inhibits B cell interactions with rhSR-A. rhSR-A that was amine-coupled to the SPR chip effectively captured human BJAB cells in solution flowing over the rhSR-A-coated chip. The B cells were able to form a stable interaction with rhSR-A. When rhSR-A was blocked with sennoside B prior to B cell injection, B cell interactions with rhSR-A were significantly inhibited, indicating that the SMI prevented SR-A interactions with B cells.
