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Model of SipC-mediated recruitment of LAMP1 on SCP. In macrophages, S. typhimurium first enter into Rab5-positive early phagosomes and then divert from the endocytic pathway and move toward the Golgi. SipC present on the SCP interacts with host Syntaxin6 to facilitate fusion with LAMP1-containing vesicles originating from Golgi.
