TABLE 1.

Efficiency of cross-seeding on Aβ alloforms as monitored by isotope-labeled NMR

Monomeric sample	Seeds	Efficiency of seeding monitored by NMR
		Aβ42	Aβ40
Pure Aβ42	Aβ40	+++	NAa
	Aβ42	+++	NA
Aβ42:Aβ40 ratio 3:7	Aβ40	+++	+++
	Aβ42	+++	+
Aβ42:Aβ40 ratio 1:9	Aβ40	+++	+++
	Aβ42	+++	+
Pure Aβ40	Aβ40	NA	+++
	Aβ42	NA	+

^a NA, not applicable.

⁺, seeding induces aggregation, +++, seeding induces aggregation very efficiently.