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. 2011 Dec 20;287(8):5979–5987. doi: 10.1074/jbc.M111.297937

FIGURE 2.

FIGURE 2.

Gene trap disruption of GW182 leads to embryonic lethality and defects in the yolk sac. A, comparison of control embryos and GW182gt/gt embryos at E9.5 and E10.5. B, H&E staining and Ki67 immunolabeling of the yolk sac identified impaired hematopoiesis, abnormal endoderm, and reduced cell proliferation in GW182gt/gt embryos at E9.5.