Table 5.

Selected down-regulated genes from 4 h microarray ranked by fold change (FC)

Gene Name	Gene Symbol	Array FC	Array p-value	qRT- PCR FC	qRT- PCR p-value
Top 5 down-regulated genes
Ischemia related factor vof-16	Vof16	−3.56	< 0.006
Distal-less 5	Dlx5	−2.02	< 0.0001	−2.95	0.0378
Ribosomal protein L7a	Rpl7a	−1.89	< 0.0006
Distal-less 1	Dlx1	−1.82	< 0.0001	−4.27	0.0001
Autism susceptibility candidate 2	Aut2	−1.82	< 0.0001	−4.52	0.0035
GABA-specific genes
Distal-less 2	Dlx2	−1.74	< 0.0001	−4.67	0.0043
Cadherin, EGF LAG seven-pass cadherin G-type receptor 3	Celsr3	−1.67	< 0.0001	−2.87	0.0024
γ-aminobutyric acid (GABA) B receptor, 1	Gabbr1	−1.51	< 0.0001	−3.15	0.0064
Distal-less 6	Dlx6	−1.43	< 0.0001
Mannosyl-glycoproteinb-1,6-N-acetyl-glucosaminyl Transferaseisozyme b	Mgat55B	−1.48	< 0.0001
LIM homeobox 6	Lhx6	−1.47	< 0.0001
Glutamate decarboxylse 2 (65 kDa)	Gad2	−1.45	< 0.0002
Glutamate decarboxylse 1 (67 kDa)	Gad1	−1.44	< 0.0002
Distal-less 6	Dlx6	−1.43	< 0.0001
Aristaless-related homeobox	Arx	−1.37	< 0.0001
Additional down-regulated genes
Glypican 2	Gpc2	−1.76	< 0.0001	−2.00	0.0050
Semaphorin 4C	Sema4C	−1.52	< 0.0001	−2.83	0.0027
Semaphorin 6C	Sema6C	−1.46	< 0.0001
Semaphorin 6B	Sema6B	−1.35	< 0.0001
Plexin 4A	Plxn4A	−1.64	< 0.0001	−2.38	0.0056
Plexin A3	PlxnA2	−1.56	< 0.0001	−5.07	0.0021
Plexin A2	PlxnA3	−1.56	< 0.0001	−5.07	0.002
Plexin A1	PlxnA1	−1.45	< 0.0001
Protocadherin GB6	PcdhgB6	−1.60	< 0.0001	−2.74	0.0024
Protocadherin 8	Pcadh8	−1.40	< 0.0001
Protocadherin 10	Pcadh10	−1.32	< 0.0004
POU class 3 homeobox 4	Pou3f4	−1.51	< 0.0001	−1.87	0.0014
POU class 3 homeobox 2	Pou3f2	−1.34	< 0.0001
POU class 3 homeobox 3	Pou3f3	−1.33	< 0.0001
Neurofilament medium polypeptide	Nefm	−1.64	< 0.0001	−3.31	0.0001
Neuron navigator 1	Nav1	−1.55	< 0.0001	−2.14	0.0055