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. Author manuscript; available in PMC: 2013 Feb 21.
Published in final edited form as: J Am Coll Cardiol. 2012 Feb 21;59(8):764–772. doi: 10.1016/j.jacc.2011.11.019

Figure 3. Lp-PLA2 mRNA and protein are upregulated in human foam-like cells in vitro.

Figure 3

Figure 3

Lp-PLA2 mRNA was significantly greater (P<0.01) in foam cells than in mature macrophages (A). Similarly, cell-associated (P=0.05) and secreted (P=0.008) Lp-PLA2 protein levels were higher in foam cells than in macrophages (B). (ANOVA and Bonferroni post-hoc tests). As monocytes were grown in suspension, protein levels were measured in monocyte cell lysates but could not be measured in media.