Table 1.
Ingredient | Diets | |||||
---|---|---|---|---|---|---|
HC | HC+7S | HC+FF | HC+RO | HC+7S+FF | HC+7S+RO | |
Casein1 | 150 | 150 | 150 | 150 | 150 | 150 |
Starch | 590.57 | 590.87 | 590.87 | 590.87 | 590.87 | 590.87 |
Sucrose | 100 | 100 | 100 | 100 | 100 | 100 |
Soybean oil | 40 | 40 | 40 | 40 | 40 | 40 |
Cellulose powder | 50 | 50 | 50 | 50 | 50 | 50 |
Mineral mixture2 | 35 | 35 | 35 | 35 | 35 | 35 |
Vitamin mixture2 | 10 | 10 | 10 | 10 | 10 | 10 |
L-Cystine | 1.8 | 1.8 | 1.8 | 1.8 | 1.8 | 1.8 |
Choline birtatrate | 2.5 | 2.5 | 2.5 | 2.5 | 2.5 | 2.5 |
Cholesterol3 | 1 | 1 | 1 | 1 | 1 | 1 |
Cholic acid1 | 5 | 5 | 5 | 5 | 5 | 5 |
Treatment (mg/kg/day) | ||||||
β-conglycinin | - | 300.0 | - | - | 300 | 300 |
Fenofibrate | - | - | 30 | - | 30 | - |
Rosuvastatin | - | - | - | 10 | - | 10 |
*HC = hypercholesterolemic diet (AIN-93 composition + 1% cholesterol and 0.5% cholic acid); HC+7S = HC diet + β-conglycinin 300 mg/Kg/day; HC+FF = HC diet + fenofibrate 30 mg/Kg/day; HC+RO = HC diet + rosuvastatin 10 mg/kg/day; HC+7S+FF = HC diet + β-conglycinin + fenofibrate 300 and 30 mg/kg/day and HC+7S+RO = HC diet + β-conglycinin + rosuvastatin 300 and 10 mg/kg/day. 1Sigma-Aldrich, Co., USA, 2PragSoluções®, Co., Brazil. 3Reagen, Co., USA.