Skip to main content
. Author manuscript; available in PMC: 2012 Aug 9.
Published in final edited form as: Nature. 2012 Jan 11;482(7384):186–191. doi: 10.1038/nature10774

Figure 1. The lid subcomplex within the holoenzyme assembly.

Figure 1

a) Negative-stain 3D reconstruction at ~15 Å resolution shows resemblance between endogenous (left) and recombinant (right) lid. b) Locations of lid (yellow) and base (cyan) within the subnanometer holoenzyme reconstruction. c) Six copies of the crystal structure of a PCI domain (PDBid: 1RZ4) are docked into the lid electron density, showing a horseshoe-shaped arrangement of the winged-helix domains. Each domain is colored according to its respective lid subunit (Fig. 2).