Table 2. LRP6 rs2302685 frequency distribution in the combined cohort samples.
| Overview groups | Overview ileal CD | |||||||||||
| all samples | IBD | Gender | Disease behaviour | Age at diagnosis | ||||||||
| controls | UC | colonic CD (L2) | ileal CD (L1+L3) | male | female | B1 | B2 | B3 | >17 | </ = 17 | ||
| TT | 1277 | 758 | 147 | 500 | 219 | 267 | 98 | 183 | 198 | 452 | 48 | |
| Genotypes (n) | CT | 609 | 364 | 83 | 263 | 112 | 152 | 58 | 76 | 126 | 228 | 35 |
| CC | 65 | 47 | 7 | 31 | 15 | 16 | 5 | 9 | 16 | 21 | 10 | |
| samples (n) | all | 1951 | 1169 | 237 | 794 | 346 | 435 | 161 | 268 | 340 | 701 | 93 |
| TT | 65.45% | 64.84% | 62.03% | 62.97% | 63.29% | 61.38% | 60.87% | 68.28% | 58.24% | 64.48% | 51.61% | |
| Frequencies | CT | 31.21% | 31.14% | 35.02% | 33.12% | 32.37% | 34.94% | 36.02% | 28.36% | 37.06% | 32.52% | 37.63% |
| CC | 3.33% | 4.02% | 2.95% | 3.90% | 4.34% | 3.68% | 3.11% | 3.36% | 4.71% | 3.00% | 10.75% | |
| Allele | T | 81.06% | 80.41% | 79.54% | 79.53% | 79.48% | 78.85% | 78.88% | 82.46% | 76.76% | 80.74% | 70.43% |
| Frequency | C | 18.94% | 19.59% | 20.46% | 20.47% | 20.52% | 21.15% | 21.12% | 17.54% | 23.24% | 19.26% | 29.57% |
The different distribution of genotypes is demonstrated for each group and subgroup: controls, UC, CD colonic CD and ileal CD. The ileal CD group was further sub-grouped according to gender, disease and age at diagnosis.