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Histological sections of native cartilage cultured for 12 h (A and C) and treated with collagenase for 12 h (B and D). Tissue section was stained with Hematoxylin and Eosin (A and B) to visualize cell nuclei (black) and connective tissue (pink), and with Safranin O and Fast Green counterstain (C and D) to visualize proteoglycans (red).
