Skip to main content
. 2012 Feb 23;7(2):e31280. doi: 10.1371/journal.pone.0031280

Table 2. Significant correlations (p) found between basal mRNA expression and the anthropometric and biochemical variables studied.

% reduction in weight % reduction in hip circumference % reduction in BMI % reduction in FFA % reduction in HOMA-IR
ACC1 SAT −0.732 (0.001) −0.624 (0.033) −0.731 (0.001) −0.459 (0.055) Ns
VAT −0.522 (0.023) −0.639 (0.010) −0.576 (0.014) Ns Ns
ACSS2 SAT −0.521 (0.039) −0.566 (0.018) −0.526 (0.052) −0.519 (0.027) Ns
VAT −0.623 (0.004) −0.619 (0.015) −0.710 (0.001) Ns Ns
ACL SAT Ns Ns Ns Ns −0.592 (0.006)
VAT Ns Ns Ns Ns Ns
PEPCK1 SAT −0.529 (0.034) −0.749 (0.002) −0.529 (0.049) Ns −0.492 (0.038)
VAT Ns Ns Ns Ns Ns

BMI: body mass index; FFA: free fatty acids; HOMA-IR: homeostasis model assessment of insulin resistance index; ACC1: acetyl-coenzyme carboxylase 1; ACSS2: acetyl-CoA synthetase short-chain family member 2; ACL: ATP citrate lyase; PEPCK1: phosphoenolpyruvate carboxykinase 1; SAT: subcutaneous adipose tissue; VAT: visceral adipose tissue; Ns: not significant. Correlation analyses were made with general linear models to adjust by age, gender, and baseline body weight and BMI as independent covariate.