Figure 2. Comparison of metabolic and viability assays.

A. P. falciparum radio-labeled hypoxanthine incorporations after 48 hours of drug treatment at concentrations corresponding to 10× IC₅₀ with artemisinin, atovaquone, and azithromycin, reported as percentages of untreated controls. Data are averages of 12 repetitions from two independent experiments B. P. falciparum viability after 48 hours of drug treatment at concentrations corresponding to 10× IC₅₀ with artemisinin, atovaquone, and azithromycin, reported as number of viable parasite, as determined by limiting serial dilutions. Data are averages of 4 independent experiments. In both panels, error bars represent the standard error of the mean (SEM).