Table 2. Effects of T6FA on ChAT and AChE activity of in hippocampus of Aβ1–40 icv C57 BL/6J mice.
Groups | ChAT (U/g protein) | AChE (U/mg protein) |
Sham | 94.84±11.22 | 0.13±0.005 |
Model | 30.00±5.95* | 0.18±0.007** |
T6FA (2 mg/kg) | 73.63±6.55## | 0.12±0.010## |
T6FA (20 mg/kg) | 61.41±7.68# | 0.13±0.012## |
Donepezil (5 mg/kg) | 59.39±8.74# | 0.13±0.005## |
Data were presented as mean ± S.E.M. n = 10;
*P<0.05,
**P<0.01 compared with sham-operated group;
P<0.05,
P<0.01 compared with model group.