Table 2. Genotype frequency distribution of CAPN10 polymorphisms among PCOS cases and controls.
SNP ID | UCSNP ID | Gene location | Genotype | PCOS Cases (N = 248) | Controls (N = 298) | *α2 (p-value) |
rs2975760 | 44 | Intron 3 | TT | 0.618 | 0.640 | 9.79 (0.007) |
TC | 0.207 | 0.271 | ||||
CC | 0.174 | 0.089 | ||||
rs3792267 | 43 | Intron 3 | GG | 0.828 | 0.824 | 2.93 (0.23) |
GA | 0.159 | 0.127 | ||||
AA | 0.012 | 0.031 | ||||
rs2975762 | 56 | Intron 4 | GG | 0.292 | 0.269 | 2.33 (0.31) |
GA | 0.483 | 0.447 | ||||
AA | 0.224 | 0.284 | ||||
rs3842570 | 19 | Intron 6 | Del/Del# | 0.229 | 0.228 | 0.09 (0.96) |
Del/Ins# | 0.459 | 0.449 | ||||
Ins/Ins# | 0.310 | 0.322 | ||||
rs5030952 | 63 | 3′UTR | CC | 0.916 | 0.913 | 0.88 (0.65) |
CT | 0.076 | 0.070 | ||||
TT | 0.008 | 0.017 |
Standard Pearson chi square value with degree of freedom = 2.
Del – Deletion.
Ins – Insertion.