Table 2.
Difference scores from placebo for parameters of the Sternberg memory scanning test and DSST
| Treatment | N | ΔSDLP | Sternberg memory scanning | DSST | |
|---|---|---|---|---|---|
| RT | Errors (%) | ||||
| Zolpidem (20 mg) | 30 | +10.41a | 0.713** | 0.344 | −0.623** |
| Alprazolam (1 mg) | 18 | +9.62a | 0.510* | 0.391 | N/D |
| Zolpidem (10 mg) | 30 | +3.35a | 0.333 | 0.256 | 0.034 |
| Diphenhydramine (50 mg, day 1) | 48 | +2.74a | 0.156 | 0.412** | N/D |
| Oxycodone/paracetamol (10/650 mg) | 18 | +1.87 | 0.375 | 0.276 | N/D |
| Diphenhydramine (50 mg, day 4) | 48 | +1.56a | 0.050 | −0.093 | N/D |
| Alcohol (BAC = 0.05%) | 29 | +1.03a | 0.261 | 0.050 | −0.070 |
| Bromfenac (50 mg) | 18 | +0.51 | −0.071 | 0.247 | N/D |
| Levocetirizine (5 mg, day 4) | 48 | +0.46 | 0.055 | −0.225 | N/D |
| Zaleplon (10 mg) | 30 | −0.45 | 0.308 | −0.300 | −0.267 |
| Zaleplon (20 mg) | 30 | +0.43 | 0.326 | −0.106 | −0.148 |
| Levocetirizine (5 mg, day 1) | 48 | +0.22 | 0.046 | −0.155 | N/D |
| Oxycodone/paracetamol (5/325 mg) | 18 | −0.65 | 0.349 | 0.313 | N/D |
| Bromfenac (25 mg) | 18 | −0.66 | 0.193 | 0.113 | N/D |
| Overall | 491 | +2.09 | 0.435** | 0.150** | −0.396** |
| N = 431 | N = 431 | N = 149 | |||
RT reaction time, SDLP standard deviation of lateral position, DSST digit symbol substitution test, N number of subjects, N/D test was not included in test battery
*p < 0.05, **p < 0.01; significance of correlation
aSDLP differed significantly from placebo