Fig. 8.

A: ozone diminishes TEER in NHBE mono- and NHBE-ASM cocultures. TEER values were determined in mono- or cocultures of NHBE cells after exposing them to ozone (0.6 ppm) or FA for 6 h. Data are represented as % changes in TEER. B: indomethacin prevents an ozone-induced decrease in TEER within NHBE monolayers. TEER values were estimated pre- and post-ozone exposure in NHBE-ASM cocultures that were treated with indomethacin (10 μM) or DMSO in the presence or absence of TNF (10 ng/ml). Data show % change in TEER from NHBE monolayers pre-and post-ozone exposure. All data are a summarization of 3 separate experiments performed in triplicate. Statistical evaluation was performed by ANOVA. P > 0.05, significant difference.