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Relative sensitivity of Nav1.4, Nav1.4/F1579A, and Nav1.4/Y1586A sodium channels to inhibition by SCI insecticides. Values are fractional inhibition after 15 min of insecticide perfusion and are derived from data in Figs. 3 and 6. Values for Nav1.4/F1579A and Nav1.4/Y1586A channels marked with asterisks were significantly different from values for inhibition of Nav1.4 channels by the same compound (one-way analysis of variance with Dunnett' post hoc analysis, P < 0.05).
