Table 3.
Univariable analysis of procedures without and with postoperative infection
| Procedures without infection (n = 310) | Procedures with infection (n = 102) | OR (95% CI) | p c | |
|---|---|---|---|---|
| Preoperative | ||||
| Age <6 monthsa | 123 (40) | 73 (72) | 3.83 (2.35–6.23) | <0.001 |
| Preoperative admission PICUa | 49 (16) | 44 (43) | 4.04 (2.46–6.64) | <0.001 |
| Low complexitya | 68 (22) | 10 (9.8) | 1.0 | <0.001 |
| Medium complexitya | 228 (74) | 74 (73) | 2.21 (1.08–4.51) | |
| High complexitya | 14 (4.5) | 18 (18) | 8.74 (3.34–23) | |
| Previous cardiac surgery | 115 (37) | 21 (20) | 0.74 (0.46–1.20) | 0.24 |
| Intraoperative | ||||
| Surgery duration >3 h | 147 (47) | 67 (66) | 2.12 (1.33–3.38) | 0.001 |
| CPB duration >2 ha | 114 (37) | 58 (57) | 2.27 (1.44–3.57) | <0.001 |
| Lowest nasal temp <25°Ca | 80 (26) | 49 (48) | 2.66 (1.67–4.23) | <0.001 |
| Postoperative | ||||
| Inotropes >48 h | 83 (27) | 69 (68) | 5.72 (3.52–9.29) | <0.001 |
| Endotracheal tube >48 h | 66 (21) | 61 (60) | 5.50 (3.40–8.89) | <0.001 |
| PICU stay >48 ha | 105 (34) | 84 (82) | 9.11 (5.20–16) | <0.001 |
| Open sternum at 48 ha | 23 (7.4) | 30 (29) | 5.20 (2.85–9.49) | <0.001 |
| Rethoracotomy | 9 (2.9) | 3 (2.9) | 1.01 (0.27–3.82) | >0.999 |
| RBC transfusion >50 mL/kga,b | 142 (46) | 83 (81) | 5.17 (2.99–8.92) | <0.001 |
| Peak glucose >10 mmol/L in first 24 ha | 151 (49) | 65 (64) | 1.85 (1.17–2.93) | 0.009 |
Variables stated as n (% of infection group)
RBC red blood cell
aThese variables were used in multivariable analysis
bSeven patients had missing data for RBC transfusion and were imputed resulting in the above values
c p values were calculated using Pearson chi-square or Fisher’s exact test, as appropriate