Fig. 4.

Effects of AMP, adenosine, inosine, ecto-5′-nucleotidase and ADA inhibitors (AMPCP and EHNA, respectively) on NO production by neutrophils stimulated with T. vaginalis. The ecto-5′-nucleotidase plays an important role on nucleoside generation. Adenosine and inosine triggered low levels on NO secretion. Bars represent the mean ± S.D. of at least three independent experiments. Data were analyzed by ANOVA followed by Tukey's test (p < 0.05). Symbols represent difference when compared with: (asterisk) neutrophils stimulated with T. vaginalis isolates; (number sign) effect of AMP