Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Silencing the P2Y2 receptor reduced the sensitivity of the cells to UTP and suppressed the sensitivity to UDP, ATPγS, BzATP. Cells in which the P2Y6 was silenced by specific siRNA still react to UDP stimulation. It is noteworthy that the negative siRNA reduced the sensitivity of the cells to the agonists. This is probable due to a nonspecific effect related to the Lipofectamine 2000 used during the transfection
